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A similar antagonism exists with copper. Zinc may be held in metallothionein reserves within microorganisms or in the intestines or liver of animals. The human dopamine transporter contains a high affinity extracellular zinc binding site which, upon zinc binding, inhibits dopamine reuptake and amplifies amphetamine -induced dopamine efflux in vitro.
The current EARs for zinc for women and men ages 14 and up is 6. RDAs are higher than EARs so as to identify amounts that will cover people with higher than average requirements.
For people ages 18 and older the PRI calculations are complex, as the EFSA has set higher and higher values as the phytate content of the diet increases.
For women, PRIs increase from 7. These PRIs are higher than the U. Food and supplement companies have until January 1, to comply with the change.
Animal products such as meat, fish, shellfish, fowl, eggs, and dairy contain zinc. The concentration of zinc in plants varies with the level in the soil.
With adequate zinc in the soil, the food plants that contain the most zinc are wheat germ and bran and various seeds, including sesame , poppy , alfalfa , celery , and mustard.
Other sources include fortified food and dietary supplements in various forms. A review concluded that zinc oxide, one of the most common supplements in the United States, and zinc carbonate are nearly insoluble and poorly absorbed in the body.
Nearly two billion people in the developing world are deficient in zinc. Groups at risk include children in developing countries and elderly with chronic illnesses.
In the United States, a federal survey of food consumption determined that for women and men over the age of 19, average consumption was 9.
The percentages below EAR increased with age. Symptoms of mild zinc deficiency are diverse. Despite some concerns,  western vegetarians and vegans do not suffer any more from overt zinc deficiency than meat-eaters.
The zinc chelator phytate , found in seeds and cereal bran , can contribute to zinc malabsorption. Species of Calluna , Erica and Vaccinium can grow in zinc metalliferous soils, because translocation of toxic ions is prevented by the action of ericoid mycorrhizal fungi.
Zinc deficiency appears to be the most common micronutrient deficiency in crop plants; it is particularly common in high-pH soils.
Substantial responses to zinc fertilization have been reported in these areas. Zinc is added to the soil primarily through the weathering of rocks, but humans have added zinc through fossil fuel combustion, mine waste, phosphate fertilizers, pesticide zinc phosphide , limestone, manure, sewage sludge, and particles from galvanized surfaces.
Excess zinc is toxic to plants, although zinc toxicity is far less widespread. Although zinc is an essential requirement for good health, excess zinc can be harmful.
Excessive absorption of zinc suppresses copper and iron absorption. The free zinc ion is a powerful Lewis acid up to the point of being corrosive.
Stomach acid contains hydrochloric acid , in which metallic zinc dissolves readily to give corrosive zinc chloride. Swallowing a post American one cent piece Disability and even deaths from excessive use of these products have been claimed.
Food and Drug Administration FDA states that zinc damages nerve receptors in the nose, causing anosmia. Reports of anosmia were also observed in the s when zinc preparations were used in a failed attempt to prevent polio infections.
The FDA said the loss of smell can be life-threatening because people with impaired smell cannot detect leaking gas or smoke, and cannot tell if food has spoiled before they eat it.
Recent research suggests that the topical antimicrobial zinc pyrithione is a potent heat shock response inducer that may impair genomic integrity with induction of PARP -dependent energy crisis in cultured human keratinocytes and melanocytes.
In , the US Mint began minting pennies coated in copper but containing primarily zinc. Zinc pennies pose a risk of zinc toxicosis, which can be fatal.
Pennies and other small coins are sometimes ingested by dogs, requiring veterinary removal of the foreign objects. The zinc content of some coins can cause zinc toxicity, commonly fatal in dogs through severe hemolytic anemia and liver or kidney damage; vomiting and diarrhea are possible symptoms.
From Wikipedia, the free encyclopedia. This article is about the metallic element. For other uses, see Zinc disambiguation. Chemical element with atomic number Zinc mining and Zinc smelting.
List of countries by zinc production. Zinc sulfate medical use. This section is transcluded from Zinc and the common cold.
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